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The original Fifth Avenue Hotel building, at 200 Fifth Avenue, was constructed on the site of what had been the Fifth Avenue Hotel, which was completed in 1859 and was demolished in 1908. The 16-story building was completed in 1909 and was originally known as the Fifth Avenue Building, which name is on the landmark clock outside the front entrance, and the interlocked initials "F.A.B." were still in the building's elevators in 2003. The architect was Robert Maynicke. Its ornate cast-iron sidewalk clock built by Hecla Iron Works in 1909 was designated a landmark by the Landmarks Preservation Commission in 1981.

The Flatiron district helped spark women’s right to vote in New York State and subsequent passage of the U.S. Constitution’s 19th Amendment in 1920. During the historic October 23, 1915, five-mile of an estimated 25,000 women who had walked uptown on Fifth Avenue.

New York City's suffrage movement, however, launched several years earlier in the Flatiron District. On February 16, 1908, a group of 23 women initiated a community march. During that wintry Saturday, the women marched from their nearby Union Square office to a public hearing at the Manhattan Trade School for Girls, then located on East 23rd Street and Lexington Avenue. One march leader proclaimed, “For the long work day, for the taxes we pay, for the laws we obey, we want something to say.”

These brave and heroic efforts by the suffragists would soon change the lives of women across New York State as they were granted the right to vote in 1917. Three years later, women gained voting rights across the United States with the passage of the 19th Amendment when it officially became part of the U.S. Constitution on August 18, 1920.

This monument to a veteran of the Mexican-American War is one of only two in Manhattan that serve as an actual mausoleum. Inside the 51-foot obelisk lie the mortal remains of General William Jenkins Worth, one of only two monuments in New York that also serve as mausoleums. The other is the much more famous Grant’s Tomb uptown.

The mausoleum is located on a small traffic island bordered by 25th Street, Broadway, and 5th Avenue. The City originally leased this site at the intersection of Broadway, Fifth Avenue, West 24th and West 25th Street in the Flatiron district of Manhattan to the United States Government for $1.00 as part of an 1807 land deal. It reverted to City ownership in 1824. Parks designated it as a public park in 1847. The monument was designed by James Goodwin Batterson, whose pedigree also included being one of the builders of the Capitol and Library of Congress in Washington, D.C. It features plaques commemorating Worth’s principal battles, a bronze relief of the General himself astride his horse, and a relic box placed in the cornerstone.

The Worth Monument is the second oldest monument in New York – the oldest being the 1856 George Washington equestrian monument at the southern end of Union Square.